Organizer
Sponsors
RedCat
Corena
FNR
Program
Wednesday January 25th, 2012
8h00 - 9h30: Registration and coffee
Keynote session:
Chair: Marc Diederich (LBMCC, Luxembourg)
| 9h30 - 10h30 |
Young-Joon Surh (College of Pharmacy, Seoul National University, Seoul, South Korea): Redox regulation of transcription factors by electrophilic lipid mediators |
| 10h30 - 11h00 | Coffee break |
Session 1: Cell death - Part I
Chair: Marc Diederich (LBMCC, Luxembourg)
| 11h00 - 11h30 |
Varsha Gandhi (M D Anderson Cancer Center, Houston, Texas, USA): Gossypol and its Analogs induce Cancer Cell Death |
11h30 - 12h00 |
Laurent Meijer (ManRos Therapeutics, ROSCOFF - FRANCE): Leucettines, a family of pharmacological inhibitors of DYRKs and CLKs derived from the marine sponge natural product Leucettamine B |
| 12h00 - 12h30 |
Arun Dharmarajan (The University of Western Australia, Perth, Australia): Cysteine Rich Domain and the Netrin Like Domain of Secreted Frizzled Related Protein 4 Inhibit Angiogenesis |
| 12h30 - 13h30 |
Workshop 1: Becton Dickinson: FACSVerse (BD FACSVerse System: Workflow Improvements) and FACSuite (Simplifying Instrument Setup and Color Compensation) |
| 14h00 - 15h00 |
Workshop 2: Essen Biosciences: Tracking time courses: novel, fully kinetic live-cell assays for apoptosis, cell death, cell migration & invasion |
| 12h30 - 14h30 | Lunch and visit of the posters |
Session 1: Cell death - Part II
Chair: Salmaan H. Inayat-Hussain (Universiti Kebangsaan Malaysia, Kuala Lumpur)
| 15h00 - 15h30 |
Salmaan H. Inayat-Hussain (Universiti Kebangsaan Malaysia, Kuala Lumpur) New insights into modulation of Redox status and apoptosis by styryllactones and stilbenes |
| 15h30 - 16h00 |
Hyeyoung Kim (Yonsei University, Seoul 120-749, Korea): Lycopene inhibits Helicobacter pylori-induced DNA damage response in gastric epithelial cells |
| 16h00 - 16h30 | Coffee break |
Session 2: Oxidative cell signaling and therapeutics
Chair: Hye-Kyung Na (Sungshin Women's University, Seoul, South Korea)
| 16h30 - 17h00 |
Lina Ghibelli (Universita' di Roma Tor Vergata, Italy): Redox-active nanoparticles in antioxidant therapy: Mechanisms and Perspectives |
| 17h00 - 17h30 |
Dominique Delmas (Inserm U866 and Université de Bourgogne, Dijon, France): Lipid rafts, DYNAMIC signaling platforms for polyphenol actions |
| 17h30 - 18h00 |
Frank Antonicelli (University of Reims, France): Oxidative stress, Inflammation and skin dysimmunity |
| 18h00 - 18h30 |
Ana Gomes (Departamento de Ciencias Quimicas, Porto, Portugal): New studies with hydroxylated flavones show scavenging activity against reactive oxygen and nitrogen species and interference with arachidonic acid metabolic pathways. |
| 18h30 - 19h00 |
Hye-Kyung Na (Sungshin Women's University, Seoul, South Korea): 15-Hydroxy- prostaglandin dehydrogenase as a potential target for chemoprevention with natural anti-inflammatory compounds. |
| 19h00 - 20h00 | Welcome reception |
Thursday January 26th, 2012
8h00 - 9h30: Registration and coffee
Session 3: Cell signaling in health and disease
Chair: Arun Dharmarajan (The University of Western Australia, Perth, Australia)
| 9h00 - 9h30 |
Shazib Pervaiz (National University of Singapore, Singapore): Superoxide anion promotes chemoresistance via inactivation of the B56δ regulatory subunit of PP2A and the accumulation of S70-phospho Bcl-2 |
| 9h30 - 10h00 |
Nijole Savickiene (Lithuanian University of Health Sciences, Medical Academy, Kaunas, Lithuania): Effect of Eleutherococcus senticoccus (Rupr et Maxim Maxim) extract on the accumulation of cadmium and amount of immune response cells in the spleen |
| 10h00 - 10h30 |
Jozefa Wesierska - Gadek (Medical University of Vienna, Vienna, Austria): PARP inhibition potentiates cytotoxicity of C-1305, a selective inhibitor of topoisomerase II, in human BRCA1-positive breast cancers cells |
| 10h30 - 11h00 | Coffee break |
Session 4: Epigenetic mechanisms and oxidative stress Part I
Chair: Wim Vanden Berghe (University Antwerp, Belgium)
| 11h00 - 11h30 |
Wim Vanden Berghe (University Antwerp, Belgium): Characterization of epigenetic plasticity of metastatic cancer cell types exposed to anti-cancer withanolides |
11h30 - 12h00 |
Ajay Goel (Baylor University Medical Center, Dallas, USA): Anti-tumor effects of curcumin and boswellic acid are mediated by epigenetic changes in colorectal cancer cells |
| 12h00 - 13h00 | Workshop 3: Promega |
| 12h30 - 14h00 | Lunch and visit of the posters |
Session 5: Transcriptional control and oxidative stress
Chair: Gautam Sethi (National University of Singapore, Singapore)
| 14h00 - 14h30 |
Gautam Sethi (National University of Singapore, Singapore): Targeting pro-inflammatory transcription factor STAT3 by agents derived from natural sources for the prevention and treatment of hepatocellular carcinoma |
| 14h30 - 15h00 |
Jacques Piette (University of Liege, Belgium): Role of the SHIP-1 phosphatase in cell death and NF-kB activation |
| 15h00 - 15h30 |
Ha-Na Lee (Seoul National University, Seoul, South Korea ): Resolvin D1 stimulates efferocytosis through p50/p50-mediated suppression of tumor necrosis factor-alpha during resolution of inflammation |
| 15h30 - 16h00 | Coffee break |
Session 6: Innovative natural compounds Part I
Chair: Robert Kiss (Université Libre de Bruxelles, Brussels, Belgium)
| 16h00 - 16h30 |
Robert Kiss (Université Libre de Bruxelles, Brussels, Belgium): Narciclasine, an Old Compound with Novel Mechanisms of Action, Is a Promising Weapon against Brain Tumors. |
| 16h30 - 17h00 |
Ki-Baik Hahm (Gachon University Lee Gil Ya Cancer and Diabetes Institute, Incheon, Korea): Anti-inflammatory, anti-mutagenic actions of omega-3 as evidenced with the potent resistance against NSAID-induced GI injury, Helicobacter pylori-gastric carcinogenesis, intestinal polyposis, and colitic cancer in fat-1 transgenic mice. |
| 17h00 - 17h30 |
Ivana Scovassi (IGM-CNR, Pavia, Italy): Berberines: new perspectives for old remedies |
| 17h30 - 18h00 |
Peter Proksch (University of Dusseldorf, Germany): New Bioactive Compounds from Marine Sponges and Fungal Endophytes |
| 20h00 - 23h00 | Gala Dinner (Hotel Sofitel) |
Friday January 27th, 2012
8h00 - 9h00: Registration and coffee
Session 7: Innovative natural compounds Part II
Chair: Chair: Robert Kiss (Free University of Brussels, Belgium)
| 9h00 - 9h30 |
Marcel Jaspars (University of Aberdeen, Scotland): From the driest to the deepest place on earth: bioactive natural products from extreme sources |
| 9h30 - 10h00 |
Claudia Cerella (LBMCC, Hôpital Kirchberg, Luxembourg): ROS-dependent JNK activation and multi-site phosphorylation of Bcl-2 link Diallyl Tetrasulfide-induced mitotic arrest to apoptosis |
| 10h00 - 10h30 |
Hasan Mukhtar (University of Wisconsin, USA): Dietary flavonoid Fistetin, a novel dual inhibitor of PI3K/AKT and mTOR for cancer management |
| 10h30 - 11h00 | Coffee break |
Session 8: Epigenetic mechanisms and oxidative stress Part II
Chair: Clarissa Gerhauser (German Cancer Research Center, Heidelberg, Germany)
| 11h00 - 11h30 |
Clarissa Gerhauser (German Cancer Research Center, Heidelberg, Germany): Nutri-Epigenetics and cancer chemoprevention |
11h30 - 12h00 |
Irfan Rahman (University of Rochester Medical Center, Rochester, NY, USA): Redox signaling and oxidative modifications of deacetylases in inflammation |
12h00 - 12h30 |
Mehdi Shakibaei (Ludwig-Maximilian-University Munich, Munich, Germany): Sirt-1 mediated deacetylation of osteoblastic transcription factor Runx2 during osteogenesis in mesenchymal stem cells in vitro |
| 12h30 - 14h00 | Lunch and visit of the posters |
Session 9: Inflammation
Chair: Bharat B. Aggarwal (The University of Texas M. D. Anderson Cancer Center, Houston, USA)
| 14h00 - 14h30 |
Bharat B. Aggarwal (The University of Texas M. D. Anderson Cancer Center, Houston, U.S.A): Targeting Inflammatory Pathways by Traditional Medicine and by Dietary Spices for Prevention and Therapy of Cancer |
| 14h30 - 15h00 |
Yong-Sang Song (Cancer Research Institute, Seoul National University, Seoul, South Korea): Cellular stress responses and cancer: new mechanistic insights on anticancer effect by phytochemicals |
| 15h00 - 15h30 |
Guy Haegeman (LEGEST, University of Gent, Belgium): A desert plant-derived compound against inflammation |
| 15h30 - 16h00 |
Norbert Latruffe (University of Burgundy, INSERM U 866, Dijon, France): Control mechanism of cell proliferation and of inflammation by resveratrol and by other polyphenols from grapevine plants. |
| 16h00 - 16h30 |
Alfonso Pompella (Scuola Medica dell'Universita di Pisa): Metabolism of S-nitrosoglutathione and expression of interleukin-8 - A possible target for modulation of lung inflammation |
| 16h30 | End of the meeting |